go to UNSW home page
UNSW logo School of Chemistry Home Page
> Contacts   > Sitemap
About the School divider Research divider Graduate Study divider Undergraduate Study divider High School Resources

Staff Profiles

Dr Justin Gooding

 

John Justin Gooding

B.Sc. (Hons) Melb. 1988, D. Phil. (Oxon) 1994, CChem, MRACI
Professor
E-mail: Justin.Gooding@unsw.edu.au
Research group web site: http://www.chem.unsw.edu.au/research/groups/gooding/

BIOGRAPHICAL DETAILS

Graduate of Oxford University (D. Phil., 1994). Postdoctoral Fellow, University of Cambridge, (1994-1996). Vice-Chancellor's Postdoctoral Research Fellow, UNSW (1997-1998). Lecturer, Flinders University of South Australia (1998). Appointed Lecturer at UNSW (1999), Senior Lecturer (2002), Associate Professor (2006), Professor (2006). NSW Young Tall Poppy Science Prize (2004), Alexander von Humboldt Fellowship (2005), University of Canterbury Erskine Fellow (2007), Royal Australian Chemical Institute Analytical Chemistry Division Lloyd Smythe Medal (2007).

RESEARCH INTERESTS

Our research group works at the boundaries of analytical chemistry, physical chemistry and biochemistry. We specialise in nanostructuring surfaces to provide them with unique functionality. Most frequently we use self-assembled monolayers for modifying the surfaces but also use nanomaterials, such as carbon nanotubes and nanoparticles, and polymers. A large part of this program is the development of biosensors. Biosensor exploit biological recognition molecules, such as enzymes, peptides and DNA, for chemical and biological analysis. The biosensors we are investigating couple the remarkable specificity of some biological molecules with a signal transducer to allow the detection of a single species in a complex media, such as blood, without sample preparation. Our target applications are for environmental monitoring and biomedical diagnostics. Other applications for our modified surfaces are for the development of biomaterials and in fundamental work on molecular electronics. Projects currently running in the laboratory are:

  1. Immunosensors for pesticide detection in environmental analysis (with a US-based biosensing company).
  2. Understanding electron transfer through a new class of molecular wires (with Professor Michael Paddon-Row, Chemistry UNSW).
  3. Porous silicon photonic crystals for biological imaging and disease diagnosis (with Professor Mike Gal, Physics UNSW and Dr. Katharina Gaus, Medicine, UNSW).
  4. Modified silicon surfaces for controlling surface interactions with cells for biomaterials applications (with Dr. Katharina Gaus, Medicine, UNSW).
  5. Peptide modified arrays for detecting multiple heavy metals on a single chip (with Professor Brynn Hibbert, Chemistry, UNSW and Dr. Jamie Quinton, Physics, Flinders University).
  6. Nanoparticle based biosensors labelling and detection in for medical diagnostics (with Professor Rose Amal, Chemical Sciences and Engineering, UNSW).
  7. Switchable surfaces (with Dr. Jason Harper, Chemistry, UNSW).
  8. DNA modified electrodes for detecting pathogens and drug compounds (with Dr. Elicia Wong, Oxford University, Dr. Wenrong Yang, Sydney University).
  9. Carbon nanotube modified electrodes for unique applications in catalysis (with Assoc. Prof. Barbara Messerle, Chemistry, UNSW).

Research Group and Outputs

The research group is typically between 10 and 15 people in size with 3 post-docs, 5-10 Ph.D. students and 3-4 honours students and visiting students. We create a supportive environment where all researchers work in teams on related projects with junior researchers being assisted by post-docs and senior Ph.D. students as well as Prof. Gooding. As our research involves a range of techniques all researchers acquire a broad range of skills but typically specialise in one or two techniques. Ph.D. students usually complete within 3½ years with 5-10 research publications. Using our team-oriented approach our research group has published 72 papers within the last five years. Representative publications are listed below.

SELECTED PUBLICATIONS

  1. W. Yang, D. Jaramillo, J.J. Gooding, D.B. Hibbert, R. Zhang, G.D. Willett, K.J. Fisher, Sub-ppt detection limits for copper ions with Gly-Gly-His modified electrodes, Chem. Commun. 1982-1983 (2001).
  2. D. Losic, J.G. Shapter, J.J. Gooding, Scanning Tunneling Microscopy Studies Of Glucose Oxidase On Gold Surface, Langmuir 18, 5422-5428 (2002).
  3. J.J. Gooding, R. Wibowo, J. Liu, W. Yang, D. Losic, S. Orbons, F.J. Mearns, J.G. Shapter, D.B. Hibbert, Protein Electrochemistry using Aligned Carbon Nanotube Arrays, J. Am. Chem. Soc. 125, 9006-9007 (2003).
  4. D. Di Giusto, W.A. Wlassoff, S. Giesebrecht, J.J. Gooding, G.C. King, Multipotential detection of electrochemical primer extension reactions on DNA self-assembled monolayers, J. Am. Chem. Soc. 126, 4120-4121 (2004).
  5. J.Q. Liu, M.N. Paddon-Row, J. Justin Gooding, Heterogeneous Electron Transfer Study for Flavin Adenine Dinucleotide (FAD) and Ferrocene through Pure and Mixed Aliphatic Alkyl SAMs on Gold Electrode, J. Phys. Chem. 108, 8460-8466 (2004).
  6. A. Chou, T. Böcking, N.K. Singh, J.J. Gooding, Demonstration of the importance of oxygenated species at the ends of carbon nanotubes on their favourable electrochemical properties, Chem. Commun. 842-844 (2005).
  7. E.L.S. Wong, E. Chow, J.J. Gooding, DNA recognition interfaces: the influence of interfacial design on the efficiency and kinetics of hybridization, Langmuir 21, 6957-6965 (2005).
  8. G.Z. Liu, J.J. Gooding, An interface comprising molecular wires and poly(ethylene glycol) spacer units self-assembled on carbon electrodes for studies of protein electrochemistry, Langmuir 22, 7421-7430 (2006).
  9. K.A. Kilian, T. Böcking, K. Gaus, J. King-Lacroise, M. Gal, J.J. Gooding, Hybrid lipid bilayers in nanostructured silicon: a biomimetic mesoporous scaffold for optical detection of cholera toxin, Chem. Commun. 1936-1938 (2007).
  10. E.L.S. Wong, J.J. Gooding, The Electrochemical Monitoring of the Perturbation of Charge Transfer through DNA by Cisplatin, J. Am. Chem. Soc. 129 8950-8951 (2007).